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ASCP MEDICAL LABORATORY TECHNICIAN - MLT(ASCP) Sample Questions:

1. Howell-Jolly bodies are composed of DNA and appear as small round ball-like inclusions inside the red cells.
Usually only one Howell-Jolly body will be present in each red cell.
Single erythrocyte inclusions which are large, round, smooth and purplish-blue staining are most likely:

A) Basophilic stippling
B) Heinz bodies
C) Cabot rings
D) Howell-Jolly bodies

2. Duffy antigens are rendered inactive by enzyme treatments since the enzyme will remove the sialic acid from the RBC membrane. This process destroys: M, N, S, s, and Duffy antigens. The process enhances the reactions for Rh, Kidd, Lewis, I, and P antigens.
When performing an antibody panel, which one of the following antigens will be rendered inactive by enzyme treatment?

A) anti-Fya
B) anti-Lua
C) anti-E
D) anti-Jka

3. Class C fires involve:
Question options:

A) grease or oil
B) flammable materials
C) electrical equipment
D) wood

4. Failure to tightly seal specimens for sweat electrolytes during collection and transport will cause:

A) decreased values due to exposure to light
B) decreased values due to exposure to air
C) increased values due to cellular contamination
D) increased values due to evaporation

5. If your reactions are strong at immediate spin (3+) and then get weaker at AHG (w+), it could mean the presence of a strong cold antibody.
Cold antibodies tend to be IgM and their optimum phase for reactivity is immediate spin. Incubation and washing of the sample may cause the agglutination that occurred at room temperature to break down. This would appear as a weaker reaction at AHG.
If the reaction strengths varied in each panel cell then that could be an indication that there are multiple antibodies present.
Your screen cells are 3+ at immediate spin and weak (W)+ at AHG. Your auto control is negative for both phases. Some of your antibody panel cells are 3+ at immediate spin and negative at AHG. What should you suspect?

A) A warm autoantibody is present
B) A cold antibody may be present
C) Bad specimen draw

Solutions: